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Signal Advance, Inc. engages in the engineering research and technology development business. The company offers Signal Advance (SA) technology that reduces signal detection delays associated with various physical sensors, as well as reduction in response time, which includes improved performance in control, intervention, and signal transmission systems. It serves biomedicine, transportation, cyber-security, industrial control system, communication, and defense markets. The company was formerly known as Biodyne Development Company, Inc and changed its name to Signal Advance, Inc. in 2007. The company was incorporated in 1992 and is based in Rosharon, Texas.